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Jiangbo Wang Selected Research

Niclosamide

1/2019Identification of novel triazole inhibitors of Wnt/β-catenin signaling based on the Niclosamide chemotype.
1/2019Niclosamide-induced Wnt signaling inhibition in colorectal cancer is mediated by autophagy.
11/2018Identification of DK419, a potent inhibitor of Wnt/β-catenin signaling and colorectal cancer growth.
1/2018Niclosamide: Beyond an antihelminthic drug.
8/2017Niclosamide-conjugated polypeptide nanoparticles inhibit Wnt signaling and colon cancer growth.
1/2017Benzimidazole inhibitors from the Niclosamide chemotype inhibit Wnt/β-catenin signaling with selectivity over effects on ATP homeostasis.
9/2015Structure-activity studies of Wnt/β-catenin inhibition in the Niclosamide chemotype: Identification of derivatives with improved drug exposure.

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Jiangbo Wang Research Topics

Disease

7Neoplasms (Cancer)
01/2019 - 06/2012
4Colonic Neoplasms (Colon Cancer)
11/2018 - 09/2015
3Colorectal Neoplasms (Colorectal Cancer)
01/2019 - 11/2018
2Inflammation (Inflammations)
12/2017 - 03/2014
2Non-alcoholic Fatty Liver Disease
08/2017 - 09/2015
2Virus Diseases (Viral Diseases)
08/2017 - 09/2015
2Breast Neoplasms (Breast Cancer)
02/2015 - 06/2012
1Parasitic Diseases (Parasitic Disease)
01/2018
1Atherosclerosis
12/2017
1Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
05/2017
1Fibrosis (Cirrhosis)
05/2017
1Cardiomyopathies (Cardiomyopathy)
05/2017
1Respiratory Insufficiency (Respiratory Failure)
09/2016
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
06/2016
1Metabolic Diseases (Metabolic Disease)
09/2015
1Glioblastoma (Glioblastoma Multiforme)
01/2015

Drug/Important Bio-Agent (IBA)

8Pharmaceutical PreparationsIBA
01/2019 - 02/2015
7NiclosamideFDA Link
01/2019 - 09/2015
6CateninsIBA
01/2019 - 09/2015
5AnthelminticsIBA
01/2019 - 09/2015
2Proteins (Proteins, Gene)FDA Link
01/2019 - 06/2012
2Biological ProductsIBA
08/2017 - 01/2017
2Tyrosine Kinase InhibitorsIBA
02/2015 - 06/2012
1Biomarkers (Surrogate Marker)IBA
01/2019
1Frizzled ReceptorsIBA
01/2019
1Mitogen-Activated Protein Kinase 3IBA
12/2017
1Perilipin-2IBA
12/2017
1LipopolysaccharidesIBA
12/2017
1PPAR gammaIBA
12/2017
1Peptides (Polypeptides)IBA
08/2017
1Galectin 3 (LGALS3)IBA
05/2017
1Doxorubicin (Adriamycin)FDA LinkGeneric
05/2017
1CollagenIBA
05/2017
1CarbohydratesIBA
06/2016
1Glucose (Dextrose)FDA LinkGeneric
06/2016
1ElementsIBA
06/2016
1Transcription Factors (Transcription Factor)IBA
06/2016
1Carrier Proteins (Binding Protein)IBA
06/2016
1ErbB Receptors (EGF Receptor)IBA
02/2015
1PerhexilineIBA
02/2015
1Bevacizumab (Avastin)FDA Link
01/2015
1fotemustine (Muphoran)IBA
01/2015
1AdipokinesIBA
03/2014
1LipidsIBA
03/2014
1VaccinesIBA
06/2012
1Tyrosine (L-Tyrosine)FDA Link
06/2012
1AntibodiesIBA
06/2012

Therapy/Procedure

2Therapeutics
02/2015 - 06/2012
1Chinese Traditional Medicine (Traditional Chinese Medicine)
05/2017
1High-Frequency Ventilation
09/2016